Donald Trump has stressed that any deal with Iran must result in the country’s “unconditional surrender”, setting maximalist war objectives for the United States.

The US president’s remarks on his Truth Social platform on Friday appear to reject the prospect of a compromise amid Iranian confirmation of diplomatic mediation to end the conflict.

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“There will be no deal with Iran except UNCONDITIONAL SURRENDER!” Trump wrote.

“After that, and the selection of a GREAT & ACCEPTABLE Leader(s), we, and many of our wonderful and very brave allies and partners, will work tirelessly to bring Iran back from the brink of destruction, making it economically bigger, better, and stronger than ever before.”

Iranian President Masoud Pezeshkian had said earlier that some countries are engaging in mediation efforts to end the war, emphasising that Iran is committed to peace in the region but prepared to defend itself.

“Mediation should address those who underestimated the Iranian people and ignited this conflict,” Pezeshkian said in a social media statement.

The conflict has spread across the Middle East, igniting Iranian attacks across the Gulf and a war between Hezbollah and Israel, resulting in a mass displacement crisis in Lebanon.

Iran has been launching missiles and drones at Israel and US interests and assets across the region. Iranian forces have also targeted energy and civilian infrastructure in Gulf countries, straining ties with the Arab world.

The violence, which saw Iran largely succeed in closing down the Strait of Hormuz, has sent oil prices soaring globally.

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Iranian officials have expressed defiance since the start of the war, stressing that they are ready for a long conflict and prepared to fend off a US ground invasion should it occur.

Iran’s Foreign Minister Abbas Araghchi said in a message to Trump on Thursday that the US plan for a “clean rapid military victory failed”.

“Your Plan B will be even bigger failure,” Araghchi wrote on X.

On Friday, Iran’s top diplomat posted a photo of the coffins of a mother and child, the apparent victims of US-Israeli attacks. “Our Brave and Powerful Armed Forces will avenge each and every Iranian mother, father, and child who has been targeted by hostile forces,” Araghchi wrote.

The war has killed at least 1,332 people in Iran, among them 181 children, according to UNICEF.

The deadliest incident was a strike on a girls’ primary school in the southern city of Minab on the opening day of the conflict, which Iranian authorities said killed about 180 pupils and staff.

The Trump administration has pushed to project confidence and dominance over Iran, with top officials saying that the US would “rain missiles”, “death and destruction” on the country.

In recent days, Trump has repeatedly said that he would like to replicate the Venezuela playbook in Iran – keeping the governing system in place but installing a leader who is friendly to US interests.

On Wednesday, Trump said he has to be “involved” in choosing the successor of Supreme Leader Ayatollah Ali Khamenei, who was assassinated in a US-Israeli attack on Saturday.

Trump told CNN later on Thursday that the situation in Iran is going to work “easily” like it did in Venezuela when Delcy Rodriguez replaced President Nicolas Maduro after he was abducted by US forces in January.

Rodriguez, who previously served as Maduro’s vice president, has allowed Washington to sell Venezuela’s oil and cut off petroleum supplies to Cuba under the threat of further US strikes.

Trump said he does not mind of the next leader of Iran is a religious figure.

“I’m saying there has to be a leader that’s going be fair and just. Do a great job. Treat the United States and Israel well, and treat the other countries in the Middle East — they’re all our partners,” he told CNN.

The supreme leader of Iran must be a Shia Muslim religious scholar.

Khamenei’s successor will be selected by an elected council of 88 members known as the Assembly of Experts.